abstract：:Idiopathic hypercalciuria, though a common cause of nephrolithiasis, has not been recognized to cause hypocalcemia and severe bone disease. We describe an adolescent with idiopathic hypercalciuria who presented initially with severe hypocalcemia and osteoporosis and this was later complicated by recurrent renal calcul...

journal_title：Nephron

authors： Wong CK,Pun KK,Tam SC,Tsui EY,Kung AW,Lam KS,Wang CC

更新日期：1992-01-01 00:00:00

abstract：:We studied the expression of Mac-1 on granulocytes (flow cytometry) from 9 patients (27 examinations) during hemodialysis with cuprophane membranes (CuM). Samples were drawn before dialysis and from the arterial and venous lines at 5, 15 and 180 min. Granulocytopenia was most pronounced after 15 min of treatment. Mac-...

journal_title：Nephron

authors： Lundahl J,Hed J,Jacobson SH

更新日期：1992-01-01 00:00:00

abstract：:Norepinephrine (NE) content, release and uptake by brain synaptosomes are reduced in chronic renal failure (CRF), and this has been attributed to the state of secondary hyperparathyroidism. The decrease in NE content in CRF could not be explained by changes in NE uptake or release since in normal circumstances, NE con...

journal_title：Nephron

authors： Islam A,Smorgorzewski M,Zayed MA,Massry SG

更新日期：1992-01-01 00:00:00

abstract：:In a 21-year-old Caucasian women with von Hippel-Lindau disease, norepinephrine-producing adrenal pheochromocytoma was identified as the underlying cause of severe hypertension. She was found to have extremely elevated levels of circulating renin and aldosterone, and she was markedly hypokalemic. Administration of cap...

journal_title：Nephron

authors： Lenz T,Thiede HM,Nussberger J,Atlas SA,Distler A,Schulte KL

更新日期：1992-01-01 00:00:00

abstract：:A 66-year-old white man presented with severe chronic renal failure. He had no past or present symptomatic glucose intolerance nor a family history of diabetes mellitus. Several fasting plasma glucose determinations, hemoglobin Alc and an oral glucose tolerance test were normal. Funduscopic ophthalmoscopy and retinal ...

journal_title：Nephron

authors： da Silva EC,Saldanha LB,Pestalozzi MS,del Bueno IJ,Barros RT,Marcondes M,Nussenzveig I

更新日期：1992-01-01 00:00:00

abstract：:The authors analysed CD4+ subset populations and particularly subset killing in order to evaluate the presence of antilymphocyte antibody against CD4+ subsets in patients with IgA nephropathy (IgA N). This study was performed in 45 patients with IgA N, 30 patients with other forms of glomerulonephritis and 30 healthy ...

journal_title：Nephron

authors： Sato M,Kino K,Nabeshima K,Koshikawa S

更新日期：1992-01-01 00:00:00

abstract：:Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) is a new autosomal form of hypophosphatemic rickets, recently described. This disease is characterized, and differs from other forms of hereditary hypophosphatemic rickets and/or osteomalacia by increased serum levels of 1,25-dihydroxyvitamin D, hypercalci...

journal_title：Nephron

authors： Tieder M,Arie R,Bab I,Maor J,Liberman UA

更新日期：1992-01-01 00:00:00

abstract：:Spontaneous allograft rupture after kidney transplantation is a rare complication usually due to an acute rejection of the interstitial type. In a 32-year-old man kidney transplantation was performed under immunosuppression with prednisolone and ciclosporin (CS). The dose of CS was 5 mg/kg body weight intravenously fo...

journal_title：Nephron

authors： Biesenbach G,Zazgornik J,Kaiser W,Grafinger P,Stuby U,Gross C,Hartl P,Brücke P

更新日期：1992-01-01 00:00:00

abstract：:The efficacy of simvastatin, a competitive inhibitor of 3-hydroxy-3-methyl glutaryl coenzyme A reductase, was investigated in 12 patients treated with continuous ambulatory peritoneal dialysis (CAPD), displaying hypercholesterolemia and moderate hypertriglyceridemia. After a 4-week placebo period, simvastatin was admi...

journal_title：Nephron

authors： Wanner C,Lubrich-Birkner I,Summ O,Wieland H,Schollmeyer P

更新日期：1992-01-01 00:00:00

abstract：:A 55-year-old woman was admitted to our hospital, complaining of general malaise, muscular weakness, anorexia and weight loss. She had a history of ingesting of a certain germanium (Ge) compound over the preceding 19 months, with a total dose of 47 g as Ge element. She was found to have renal failure (blood urea nitro...

journal_title：Nephron

authors： Takeuchi A,Yoshizawa N,Oshima S,Kubota T,Oshikawa Y,Akashi Y,Oda T,Niwa H,Imazeki N,Seno A

更新日期：1992-01-01 00:00:00

abstract：:The course of left ventricular hypertrophy was investigated in anemic hemodialysis patients treated with recombinant human erythropoietin (r-huEPO). 12 patients, aged 60.8 +/- 9.9 years (mean +/- SD) were treated for 18.8 +/- 2.7 months. Left ventricular size was estimated by echocardiography performed before treatmen...

journal_title：Nephron

authors： Zehnder C,Zuber M,Sulzer M,Meyer B,Straumann E,Jenzer HR,Blumberg A

更新日期：1992-01-01 00:00:00

abstract：:The number of mast cells in the skin was evaluated in 25 patients with end-stage renal failure on different treatment modality (conservative, hemodialysis and peritoneal dialysis). According to the presence of pruritus, uremic patients were divided into two groups: group A, 13 patients with diffuse pruritus, and group...

journal_title：Nephron

authors： Dimković N,Djukanović L,Radmilović A,Bojić P,Juloski T

更新日期：1992-01-01 00:00:00

abstract：:A 41-year-old woman was admitted to the hospital because of renal failure requiring hemodialysis treatment. Renal biopsy revealed active chronic interstitial nephritis. Renal function nearly normalized after removal of a copper-containing intrauterine device (IUCD). We conclude that copper-IUCDs may lead to renal fail...

journal_title：Nephron

authors： Hocher B,Keller F,Krause PH,Gollnick H,Oelkers W

更新日期：1992-01-01 00:00:00

abstract：:Renal handling of urate, xanthine and hypoxanthine was studied in a hypouricemic patient who had increased plasma concentrations of xanthine and hypoxanthine. The patient, a 50-year-old man, had been suffering from Parkinson's disease, while neither systemic disorders nor particular renal diseases known to affect plas...

journal_title：Nephron

authors： Kawachi M,Kono N,Kiyokawa H,Mineo I,Nakajima H,Shimizu T,Yorifuji S,Kuwajima M,Tarui S

更新日期：1992-01-01 00:00:00

abstract：:329 patients were evaluated from 1978 to 1990. 40 new cases of non-A non-B hepatitis were observed, all regarding patients on hemodialysis. Since the beginning of 1989, we introduced measures to limit the diffusion of the virus: reduction to a minimum of blood transfusions and a new disinfection protocol for monitors,...

journal_title：Nephron

authors： La Russa A,Bufano G,Cauzzi L,Pecchini P

更新日期：1992-01-01 00:00:00

abstract：:Thymopentine is a synthetic immunomodulator that positively affects T-lymphocyte maturation, reproduction and differentiation. In elderly uremic patients nonresponders to hepatitis B vaccine, the administration of this drug has been shown to improve the response to the new vaccination. ...

journal_title：Nephron

authors： Melappioni M,Baldassari M,Baldini S,Radicioni R,Panichi N

更新日期：1992-01-01 00:00:00

abstract：:Because of the great problem of viral hepatitis in hemodialysis patients, the Italian Society of Nephrology decided to perform a national epidemiologic survey. We contacted 467 nephrological centers by a questionnaire which let us have information on 25,746 uremic patients: 18,338 on HD, 2,250 on PD and 5,176 with kid...

journal_title：Nephron

authors： Mioli VA,Balestra E,Bibiano L,Carletti P,Della Bella S,Fanciulli E,Gaffi G,Marinelli R,Perilli R,Ricciatti AM

更新日期：1992-01-01 00:00:00

abstract：:We report a case of visceral leishmaniasis in a 38-year-old renal transplant recipient living in an endemic country. Antimonial derivatives induced a rapid remission. A review of the literature disclosed 8 cases of this association with a fatal fulminant outcome in 5 cases. We suggest that the specific immunosuppressi...

journal_title：Nephron

authors： Moulin B,Ollier J,Bouchouareb D,Purgus R,Olmer M

更新日期：1992-01-01 00:00:00

abstract：:The possible role of altered renal prostaglandin metabolism in the generation of post-obstruction diuresis (POD) was examined in 16 adult male Sprague-Dawley rats. Inhibition of cyclooxygenase by the administration of a combination of two nonsteroidal anti-inflammatory drugs (NSAID), meclofenamate and indomethacin in ...

journal_title：Nephron

authors： Kauker ML,Zawada ET

更新日期：1992-01-01 00:00:00

abstract：:The Center for Devices and Radiological Health, in collaboration with the Department of Veterans Affairs Medical Center, Brooklyn, N.Y., conducted a multi-center, multi-institutional study of the seroprevalence of antibodies to the human immunodeficiency virus (HIV) among dialysis workers. Seven dialysis units and 112...

journal_title：Nephron

authors： Berlyne G,Kaczmarek RG,Hamburger S,Hamilton P,Moore RM Jr,Charney AN,Kahn T,Gruber M,Kaufman CE,Goffinet J

更新日期：1992-01-01 00:00:00

abstract：:We investigated changes in the levels of mRNA transcripts encoding types I and IV collagen in the kidney following the administration of ciclosporin (CS) in mice. Daily doses of CS increased the levels of mRNAs encoding collagen types I and IV in whole kidneys harvested 4 weeks after treatment. At this time point, nei...

journal_title：Nephron

authors： Wolf G,Neilson EG

更新日期：1992-01-01 00:00:00

abstract：:Following successful kidney transplantation, renal anemia is gradually corrected during the first 3-4 months. Serum erythropoietin (EPO) levels are increased after the first postoperative day following grafting. In this study, the serum EPO levels in the early posttransplant phase were investigated in 8 living-donor a...

journal_title：Nephron

authors： Goch J,Birgegård G,Wikström B,Tufveson G,Danielson BG

更新日期：1992-01-01 00:00:00

abstract：:In earlier studies, we have shown that induction of passive Heymann nephritis (PHN) by intrarenal infusion of anti-Fx1A antibodies provokes an immediate fall in renal blood flow (RBF) and glomerular filtration rate (GFR). This was probably mediated via the complement system, as infusion of the F(ab')2 fraction of anti...

journal_title：Nephron

authors： Sekse I,Iversen BM,Daha MR,Ofstad J

更新日期：1992-01-01 00:00:00

abstract：:It is most important to differentiate destructive spondyloarthropathy (DSA) from vertebral osteomyelitis (VOM), both showing similar roentgenographic findings and evaluate the spinal involvement of DSA. Magnetic resonance imaging (MRI) is useful for morphological and biochemical analysis of spinal lesions, but few stu...

journal_title：Nephron

authors： Maruyama H,Gejyo F,Arakawa M

更新日期：1991-01-01 00:00:00

abstract：:We found a strain of nonobese, nondiabetic (NON) mice which has spontaneous lipid deposition in glomerular capillary lumina. This strain was developed together with a diabetic strain of nonobese diabetic (NOD) mice for the generation of mouse models of diabetes mellitus. In the NON strain, contrary to the name, impair...

journal_title：Nephron

authors： Watanabe Y,Itoh Y,Yoshida F,Koh N,Tamai H,Fukatsu A,Matsuo S,Hotta N,Sakamoto N

更新日期：1991-01-01 00:00:00

abstract：:The decarboxylation and transamination reactions of glyoxylate, which divert this precursor from oxalate formation, have been investigated. Decarboxylation of glyoxylate is synergistic with 2-oxoglutarate and catalysed by 2-oxoglutarate:glyoxylate carboligase which co-chromatographs with the 2-oxoglutarate dehydrogena...

journal_title：Nephron

authors： Bais R,Rofe AM,Conyers RA

更新日期：1991-01-01 00:00:00

abstract：:The effects of each of several tannins purified from Rhei Rhizoma on serum constituents were investigated in rats with adenine-induced renal failure. Blood levels of urea nitrogen, methylguanidine (MG), and guanidinosuccinic acid (GSA) were significantly decreased in rats given (-)-epicatechin 3-O-gallate at a dose of...

journal_title：Nephron

authors： Yokozawa T,Fujioka K,Oura H,Nonaka G,Nishioka I

更新日期：1991-01-01 00:00:00

abstract：:Serum and urinary concentrations of NCl, the non collagenous globular domain of collagen IV, were used as markers for turnover of basement membranes. NCl levels were studied in membranous glomerulonephritis and diabetic nephropathy. Thirteen patients with membranous glomerulonephritis and 8 insulin-dependent diabetic ...

journal_title：Nephron

authors： Torffvit O,Agardh CD,Alm P,Wieslander J

更新日期：1991-01-01 00:00:00

abstract：:Oral phosphatidylcholine at 900 mg/day was given to 4 patients with high lymph absorption for 8 weeks. Fluid and solute transfer before and after treatment were compared to 4 similar controls given placebo. None of the patients had overt ultrafiltration problems. After treatment, overnight peritoneal effluent phosphol...

journal_title：Nephron

authors： Chan PC,Tam SC,Robinson JD,Yu L,Ip MS,Chan CY,Cheng IK

更新日期：1991-01-01 00:00:00

abstract：:The clinical profile of a patient with a 15 years' evolution of acne conglobata developing systemic amyloidosis with severe renal involvement is described, and the possible influence of suppurative skin foci surgical excision on the rapid progression to terminal renal failure is discussed. This etiological cause of se...

journal_title：Nephron

authors： Naya MT,Soria C,Quereda C,Orte L,Romero R,Ortuño J

更新日期：1991-01-01 00:00:00

abstract：:To reassess the reported protective effects of verapamil in renal ischaemia, we perfused the left kidney of uninephrectomized female Wistar rats with verapamil (0.1 and 1.0 mg/kg) immediately prior to clamping the renal artery for 60 min. When compared to controls, both doses of verapamil failed to afford protection w...

journal_title：Nephron

authors： Bock HA,Brunner FP,Torhorst J,Thiel G

更新日期：1991-01-01 00:00:00

abstract：:To determine whether the chelation of aluminium enhances the haemopoietic response to recombinant human erythropoietin (r-HuEPO), desferrioxamine (DFO) at a dose of 20-30 mg/kg was given to 7 of 17 transfusion-dependent haemodialysis patients treated with r-HuEPO (40 units/kg/dialysis i.v.). The two randomly allocated...

journal_title：Nephron

authors： Roger SD,Stewart JH,Harris DC

更新日期：1991-01-01 00:00:00

abstract：:A few cases of nephrotic syndrome with the glomerular deposition of an amyloid-like material which did not stain with Congo red have been documented. But extrarenal deposits have not been previously reported in this disease. We describe here a case of nephrotic syndrome associated with the deposition of an amyloid-lik...

journal_title：Nephron

authors： Ozawa K,Yamabe H,Fukushi K,Osawa H,Chiba N,Miyata M,Seino S,Inuma H,Sasaki T,Yoshikawa S

更新日期：1991-01-01 00:00:00

abstract：:Males on long-term dialysis tend to develop more severe forms of acquired cystic disease of the kidney than females. The severity of the disease is unaffected by therapeutic modality, either hemodialysis or CAPD, however, cystic transformation becomes less extensive after successful renal transplantation. The fundamen...

journal_title：Nephron

authors： Ishikawa I

更新日期：1991-01-01 00:00:00

abstract：:Tubular necrosis elicits a process of renal tissue repair characterized by an increase of cell turnover in tubular epithelium. The present study was undertaken to examine the distribution of epidermal growth factor (EGF) and/or of its larger precursor proEGF in the kidney undergoing tubular regeneration. Sprague-Dawle...

journal_title：Nephron

authors： Nonclercq D,Toubeau G,Lambricht P,Heuson-Stiennon JA,Laurent G

更新日期：1991-01-01 00:00:00

abstract：:Serum ferritin level has been shown by many investigators to be a good indicator of bone marrow iron stores in normal subjects. Although this correlation may hold in some pathological situations, it is lost in others. In leukemia a dissociation has been observed between serum ferritin levels and bone marrow iron store...

journal_title：Nephron

authors： Nuwayri-Salti N,Jabre F,Saab G,Daouk M,Salem Z

更新日期：1991-01-01 00:00:00

abstract：:To evaluate the patterns of renal images and the diagnostic value as a screening test of the whole-body bone and renal scintigraphy with technetium-99m-methylene diphosphonate (99mTc-MDP) or -pyrophosphate (99mTc-PYP), we performed bone scintigraphy in 6 patients with acute renal failure (ARF) with severe loin pain an...

journal_title：Nephron

authors： Han JS,Kim YG,Kim S,Lee MC,Lee JS,Kim SH

更新日期：1991-01-01 00:00:00

abstract：:The ability of cultured peripheral-blood mononuclear cells (PBMC) to release interleukin-1 alpha and beta (IL-1 alpha, IL-1 beta) in response to concanavalin A (con A) was investigated in patients with chronic renal failure (CRF) and in renal transplant recipients. Mean IL-1 alpha level released by PBMC of healthy sub...

journal_title：Nephron

authors： Kang XX,Hirano T,Oka K,Tamaki T,Sakurai E,Kaji N,Yoshida M,Kozaki M

更新日期：1991-01-01 00:00:00

abstract：:The present prospective study was conducted in order to establish the relationship between complement activation and stimulation of phagocyte oxidative metabolism observed in long-term hemodialysis (HD) patients during the early phase of dialysis with cellulosic membranes. Two groups of 10 randomized (HD) patients tre...

journal_title：Nephron

authors： Descamps-Latscha B,Goldfarb B,Nguyen AT,Landais P,London G,Haeffner-Cavaillon N,Jacquot C,Herbelin A,Kazatchkine M

更新日期：1991-01-01 00:00:00

abstract：:Effect of the immunosuppressive agent, ciclosporin (CS), on bovine serum albumin (BSA) nephritis in rats was evaluated. Eight weeks after immunization, 19 male Wistar rats received a daily intravenous dose of BSA (2 mg). Two weeks later, 11 rats received BSA and an oral dose of CS (10 mg/kg), and 8 rats received only ...

journal_title：Nephron

authors： Fujita M,Iida H,Asaka M,Izumino K,Takata M,Sasayama S

更新日期：1991-01-01 00:00:00